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Review
. 2014 Nov;25(11):1453-62.
doi: 10.1007/s00192-014-2452-4. Epub 2014 Jul 8.

Neural control of lower urinary tract and targets for pharmacological therapy

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Review

Neural control of lower urinary tract and targets for pharmacological therapy

Maria Augusta T Bortolini et al. Int Urogynecol J. 2014 Nov.

Abstract

Studies on the physiology and pharmacology of the lower urinary tract have brought new information and concepts about the complex neural control of micturition. There are many mechanisms, some proven and others not yet completely understood, in which pharmacological agents may act facilitating the filling, storage, and emptying of the bladder. This review describes the peripheral innervation and the main pathways involved in lower urinary tract control. It also presents potential targets for the treatment of voiding dysfunctions.

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