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Case Reports
. 2014 Jul;75(4):251-63.
doi: 10.1007/s00056-014-0216-x. Epub 2014 Jul 9.

Dental and craniofacial characteristics in a patient with Hutchinson-Gilford progeria syndrome

Christoph Reichert  1 , Lina Gölz, Werner Götz, Michael Wolf, James Deschner, Andreas Jäger
Affiliations
Case Reports

Dental and craniofacial characteristics in a patient with Hutchinson-Gilford progeria syndrome

Christoph Reichert et al. J Orofac Orthop. 2014 Jul.

Abstract

The Hutchinson-Gilford progeria syndrome (HGPS) is an exceptionally rare medical disorder caused by mutations in the lamin A/C gene. Affected patients display typical features of premature aging. Beside general medical disorders, these patients have several specific features related to the craniofacial phenotype and the oral cavity. In this article, the dental and craniofacial characteristics of a 9-year-old girl with HGPS are presented. It is the first report addressing orthodontic tooth movement and microbiological features in a HGPS patient. We describe and discuss pathologic findings and provide a detailed histology of the teeth which had to be extracted during initial treatment.

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