Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2014 Aug;16(8):1025-6.
doi: 10.1093/neuonc/nou121. Epub 2014 Jul 6.

Intratumoral heterogeneity and intraclonal plasticity: from warburg to oxygen and back again

Affiliations
Editorial

Intratumoral heterogeneity and intraclonal plasticity: from warburg to oxygen and back again

Charles A Conrad et al. Neuro Oncol. 2014 Aug.
No abstract available

PubMed Disclaimer

Comment on

  • See the article by Saga et al, on pages 1048–1056

References

    1. Koppenol WH, Bounds PL, Dang CV. Otto Warburg's contributions to current concepts of cancer metabolism. Nature reviews. Cancer. 2011;11(5):325–337. - PubMed
    1. Hitosugi T, Zhou L, Elf S, et al. Phosphoglycerate mutase 1 coordinates glycolysis and biosynthesis to promote tumor growth. Cancer cell. 2012;22(5):585–600. - PMC - PubMed
    1. Vander Heiden MG, Locasale JW, Swanson KD, et al. Evidence for an alternative glycolytic pathway in rapidly proliferating cells. Science. 2010;329(5998):1492–1499. - PMC - PubMed
    1. Rong Y, Durden DL, Van Meir EG, Brat DJ. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. Journal of neuropathology and experimental neurology. 2006;65(6):529–539. - PubMed
    1. Ward PS, Thompson CB. Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer cell. 2012;21(3):297–308. - PMC - PubMed

Publication types