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Case Reports
. 2014 May 13;6(2):5343.
doi: 10.4081/rt.2014.5343.

Clear cell hidradenoma of breast mimicking atypical breast lesion: a diagnostic pitfall in breast cytology

Shelly Sehgal  1 , Prashant Goyal  1 , Soumyesh Ghosh  1 , Deepti Mittal  1 , Awanindra Kumar  1 , Sompal Singh  1
Affiliations
Case Reports

Clear cell hidradenoma of breast mimicking atypical breast lesion: a diagnostic pitfall in breast cytology

Shelly Sehgal et al. Rare Tumors. .

Abstract

Clear cell hidradenoma (CCH) is an uncommon skin adnexal tumor arising from eccrine glands. Although several kind of skin adnexal tumors arise in the breast tissue, CCH of the breast is an extremely rare entity. Failure to identify its cytomorphologic features and rarity of this tumor may lead to misdiagnosis on fine needle aspiration cytology. Hereby we report a case of 30-year-old female who presented with painless lump in left breast since 10 months. Fine needle aspiration cytology of lump yielded fluid material. On May-Grunwald-Giemsa stained smears, a possibility of atypical breast lesion was considered and patient was advised a biopsy examination. Final diagnosis of CCH was made on histopathologic examination. Awareness of cytomorphologic features of breast CCH will prevent misdiagnosis as malignant or atypical breast lesions and will allow for correct management of the patients.

Keywords: atypical breast lesion; breast cytology; clear cells; hidradenoma; skin adnexal tumor.

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Conflict of interest statement

Conflict of Interests: the authors declare no potential conflict of interests.

Figures

Figure 1.
Figure 1.
Cytology smear showing cohesive cluster with nuclear crowding and mild nuclear atypia (May-Grunwald-Giemsa stain, 40×).
Figure 2.
Figure 2.
Cytology smear showing cohesive cluster of cells with moderate eosinophilic cytoplasm and mild nuclear pleomorphism (May-Grunwald-Giemsa stain, 40×).
Figure 3.
Figure 3.
The tumor is composed of two cell population, one with small eccentric nucleus and clear cytoplasm, and others having round to oval nucleus and eosinophilic cytoplasm (Hematoxylin and Eosin stain, 10× and 40× inset).
See this image and copyright information in PMC

References

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