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Observational Study
. 2014 Jul;109(4):499-501.
doi: 10.1590/0074-0276130563. Epub 2014 Jul 3.

Varicella zoster virus reactivation during or immediately following treatment of tegumentary leishmaniasis with antimony compounds

Andrea Barbieri Barros  1 , Alex Miranda Rodrigues  1 , Mariane Pereira Batista  1 , Sidney Munhoz Junior  1 , Marcia Hueb  1 , Cor Jesus Fontes  1
Affiliations
Observational Study

Varicella zoster virus reactivation during or immediately following treatment of tegumentary leishmaniasis with antimony compounds

Andrea Barbieri Barros et al. Mem Inst Oswaldo Cruz. 2014 Jul.

Abstract

Antimony compounds are the cornerstone treatments for tegumentary leishmaniasis. The reactivation of herpes virus is a side effect described in few reports. We conducted an observational study to describe the incidence of herpes zoster reactivation during treatment with antimony compounds. The global incidence of herpes zoster is approximately 2.5 cases per 1,000 persons per month (or 30 cases per 1,000 persons per year). The estimated incidence of herpes zoster in patients undergoing antimony therapy is higher than previously reported.

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Figures

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Cumulative probability of the development of herpes zoster during treatment with antimony compounds.
See this image and copyright information in PMC

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