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Case Reports
. 2014 Aug;124(2 Pt 2 Suppl 1):413-415.
doi: 10.1097/AOG.0000000000000339.

Successful in utero intervention for bilateral renal agenesis

Jessica L Bienstock  1 , Meredith L Birsner, Fred Coleman, Nancy A Hueppchen
Affiliations
Case Reports

Successful in utero intervention for bilateral renal agenesis

Jessica L Bienstock et al. Obstet Gynecol. 2014 Aug.

Abstract

Background: We report a case of bilateral renal agenesis treated with serial amnioinfusion in which the newborn survived the newborn period and was able to undergo peritoneal dialysis as a bridge to planned renal transplantation.

Case: A 34-year-old woman, gravida 1 para 0, presented at 23 1/7 weeks of gestation with a diagnosis of anhydramnios and bilateral renal agenesis. The patient underwent weekly serial amnioinfusion with the goal of improving fetal pulmonary development. At 28 weeks of gestation, the patient delivered a live newborn who required minimal respiratory support. The neonate is currently 9 months old and is undergoing daily peritoneal dialysis.

Conclusion: Serial amnioinfusion appears to have mitigated the severe pulmonary compromise that has, in the past, led to the death of newborns with bilateral renal agenesis.

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References

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