Aging: the blurry line between life and death
- PMID: 25004366
- DOI: 10.1016/j.cub.2014.05.057
Aging: the blurry line between life and death
Abstract
Although historically reactive oxygen species have been implicated as a potential cause of ageing, recent evidence suggests that a modest increase in oxidants can actually extend lifespan. A new study suggests that, in Caenorhabditis elegans, reactive oxygen species regulate longevity through a pathway classically linked to apoptosis.
Copyright © 2014 Elsevier Ltd. All rights reserved.
Comment on
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The intrinsic apoptosis pathway mediates the pro-longevity response to mitochondrial ROS in C. elegans.Cell. 2014 May 8;157(4):897-909. doi: 10.1016/j.cell.2014.02.055. Cell. 2014. PMID: 24813612 Free PMC article.
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