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Review
. 2014 Sep;105(3):e10-5.
doi: 10.1016/j.diabres.2014.06.009. Epub 2014 Jun 23.

Comparison of repaglinide and metformin versus metformin alone for type 2 diabetes: a meta-analysis of randomized controlled trials

Jinjin Yin  1 , Houliang Deng  1 , Shumin Qin  2 , Waijiao Tang  3 , Lu Zeng  3 , Benjie Zhou  4
Affiliations
Review

Comparison of repaglinide and metformin versus metformin alone for type 2 diabetes: a meta-analysis of randomized controlled trials

Jinjin Yin et al. Diabetes Res Clin Pract. 2014 Sep.

Abstract

We conducted a meta-analysis to compare the efficacy and safety of repaglinide plus metformin with metformin alone on type 2 diabetes. Twenty-two studies were included in this meta-analysis. Results showed combination therapy was safe and could gain better outcomes in glycemic control. Well-designed studies are required to confirm this conclusion.

Keywords: Combination therapy; Meta-analysis; Metformin; Repaglinide; Type 2 diabetes mellitus.

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