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Case Reports
. 2014;6(1):39-42.

Complete congenital foetal heart block: a case report

M Dey  1 , T Jose  1 , A Shrivastava  1 , R D Wadhwa  1 , R Agarwal  1 , V Nair  1
Affiliations
Case Reports

Complete congenital foetal heart block: a case report

M Dey et al. Facts Views Vis Obgyn. 2014.

Abstract

Congenital heart block (CHB) is the most severe manifestation of neonatal lupus which can develop into a lethal atrioventricular (AV) block. Complete congenital foetal heart block related to maternal anti-Ro/SSA autoanti-bodies typically develops between 20 and 24 weeks of gestation. CHB with a structurally normal heart is frequently associated with maternal autoantibodies to Ro/SSA and La/SSB. We are presenting a case of foetal complete CHB with high maternal Ro/SSA and La/SSB titre with favourable outcome.

Keywords: Congenital heart block; Dexamethasone; La/SSB; Ro/SSA; SLE.

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Figures

Fig. 1
Fig. 1. Doppler showing foetal heart rate of 66/min
Fig. 2
Fig. 2. Post delivery ECG showing heart rate of 54/min
See this image and copyright information in PMC

References

    1. Buyon JP, Clancy RM, Fridman DM. Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal/foetal dyad at risk. J Intern Med. 2009;265:653–662. - PMC - PubMed
    1. Buyon JP, Clancy RM, Friedman DM. Cardiac Manifestations of Neonatal Lupus Erythematosus: guidelines to management integrating integrating clues from the bench and bedside. Nat Clin Pract Rheumatol. 2009;5:139–148. - PubMed
    1. Buyon JP, Hiebert R, Copel J, et al. Autoimmune-associated congenital heart block: Mortality, morbidity, and recurrence rates obtained from a national neonatal lupus registry. J Am Coll Cardiol. 1998;31:1658–1666. - PubMed
    1. Carolis SD, Salvi S, Botta A, et al. Which Intrauterine Treatment for Autoimmune Congenital Heart Block? Open Autoimmunity Journal. 2010;2:1–10.
    1. Chalumeau N, Amoura Z, Le Thi Hong D, et al. Questions about dexamethasone use for the prevention of anti-SSA related congenital heart block. Ann Rheum Dis. 2003;62 - PMC - PubMed

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