Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2015 Jan;26(1):3-5.
doi: 10.1681/ASN.2014060567. Epub 2014 Jul 10.

Antagonism of canonical Wnt/β-catenin signaling: taking RAS blockade to the next level?

Jürgen Floege  1
Affiliations
Editorial

Antagonism of canonical Wnt/β-catenin signaling: taking RAS blockade to the next level?

Jürgen Floege. J Am Soc Nephrol. 2015 Jan.
No abstract available

Keywords: ACE inhibitors; angiotensin; chronic kidney disease; fibrosis; renin angiotensin system.

PubMed Disclaimer

Comment on

References

    1. Navar LG, Harrison-Bernard LM, Wang CT, Cervenka L, Mitchell KD: Concentrations and actions of intraluminal angiotensin II. J Am Soc Nephrol 10[Suppl 11]: S189–S195, 1999 - PubMed
    1. Zhou L, Li Y, Hao S, Zhou D, Tan RJ, Nie J, Hou FF, Kahn M, Liu Y: Multiple genes of the renin-angiotensin system are novel targets of Wnt/β-catenin signaling. J Am Soc Nephrol 26: 107–120, 2015 - PMC - PubMed
    1. Emami KH, Nguyen C, Ma H, Kim DH, Jeong KW, Eguchi M, Moon RT, Teo JL, Kim HY, Moon SH, Ha JR, Kahn M: A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]. Proc Natl Acad Sci U S A 101: 12682–12687, 2004 - PMC - PubMed
    1. Hao S, He W, Li Y, Ding H, Hou Y, Nie J, Hou FF, Kahn M, Liu Y: Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis. J Am Soc Nephrol 22: 1642–1653, 2011 - PMC - PubMed
    1. Henderson WR, Jr, Chi EY, Ye X, Nguyen C, Tien YT, Zhou B, Borok Z, Knight DA, Kahn M: Inhibition of Wnt/beta-catenin/CREB binding protein (CBP) signaling reverses pulmonary fibrosis. Proc Natl Acad Sci U S A 107: 14309–14314, 2010 - PMC - PubMed

LinkOut - more resources