HIV/AIDS. Persistence by proliferation?

Affiliations

¹ Departments of Medicine, Microbiology and Immunology, and Epidemiology, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Chapel Hill, NC 27599-7042, USA. dmargo@med.unc.edu bushman@mail.med.upenn.edu.
² Perelman School of Medicine, 3610 Hamilton Walk, Philadelphia, PA 19104, USA. dmargo@med.unc.edu bushman@mail.med.upenn.edu.

Comment

David Margolis et al. Science. 2014.

. 2014 Jul 11;345(6193):143-4.

doi: 10.1126/science.1257426.

¹ Departments of Medicine, Microbiology and Immunology, and Epidemiology, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Chapel Hill, NC 27599-7042, USA. dmargo@med.unc.edu bushman@mail.med.upenn.edu.
² Perelman School of Medicine, 3610 Hamilton Walk, Philadelphia, PA 19104, USA. dmargo@med.unc.edu bushman@mail.med.upenn.edu.

No abstract available

Comment on

HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells.
Maldarelli F, Wu X, Su L, Simonetti FR, Shao W, Hill S, Spindler J, Ferris AL, Mellors JW, Kearney MF, Coffin JM, Hughes SH. Maldarelli F, et al. Science. 2014 Jul 11;345(6193):179-83. doi: 10.1126/science.1254194. Epub 2014 Jun 26. Science. 2014. PMID: 24968937 Free PMC article.
HIV latency. Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection.
Wagner TA, McLaughlin S, Garg K, Cheung CY, Larsen BB, Styrchak S, Huang HC, Edlefsen PT, Mullins JI, Frenkel LM. Wagner TA, et al. Science. 2014 Aug 1;345(6196):570-3. doi: 10.1126/science.1256304. Epub 2014 Jul 10. Science. 2014. PMID: 25011556 Free PMC article.