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. 2014 Sep 4;50(68):9745-8.
doi: 10.1039/c4cc02966f.

NIR-triggered drug release from switchable rotaxane-functionalized silica-covered Au nanorods

Menghuan Li  1 , Hong Yan, Cathleen Teh, Vladimir Korzh, Yanli Zhao
Affiliations

NIR-triggered drug release from switchable rotaxane-functionalized silica-covered Au nanorods

Menghuan Li et al. Chem Commun (Camb). .

Abstract

An NIR-triggered drug delivery system was developed by capping photo-switchable azobenzene-based rotaxane onto Au nanorod-mesoporous silica core-shell hybrids. Drug release from the nanocarrier in zebrafish embryo models could be controlled remotely under NIR irradiation, showing significant drug spreading to the adjacent tissues.

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