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Case Reports
. 2014 Apr-Jun;10(2):374-6.
doi: 10.4103/0973-1482.136662.

Vimentin positive acantholytic penile squamous cell carcinoma with rhabdoid features

Ramesh Y Chavan, Akshay Bali  1 , K S Savita, J V Chethan
Affiliations
Free article
Case Reports

Vimentin positive acantholytic penile squamous cell carcinoma with rhabdoid features

Ramesh Y Chavan et al. J Cancer Res Ther. 2014 Apr-Jun.
Free article

Abstract

Acantholytic variant of penile squamous cell carcinoma (SCC) is an exceedingly rare and associated with bad prognosis. Histologically it mimics angiosarcoma due to pseudovascular spaces. Vimentin immunopositivity in such cases represent epithelial to mesenchymal transition manifested by cellular discohesion. We describe a case of vimentin positive acantholytic penile SCC in a 55-year-old patient.

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