An insight into the possibilities of fibroblast growth factor in periodontal regeneration
- PMID: 25024539
- PMCID: PMC4095618
- DOI: 10.4103/0972-124X.134560
An insight into the possibilities of fibroblast growth factor in periodontal regeneration
Abstract
Periodontitis is caused by bacterial biofilms and is modulated by a variety of risk factors. The periodontal ligament comprises heterogeneous cell populations which are lost in the disease process. A variety of regenerative therapies, such as bone grafts, guided tissue regeneration treatment, application of enamel matrix derivative, have been introduced, with some success in periodontal tissue regeneration. Topical application of recombinant cytokines is now one of the most effective methods to stimulate stem cells. Researchers are now exploring the potential applications and uses of fibroblast growth factor in periodontal regeneration.
Keywords: Fibroblast growth factor; periodontal regeneration; stem cells.
Conflict of interest statement
Similar articles
-
Human periodontal fibroblast response to enamel matrix derivative, amelogenin, and platelet-derived growth factor-BB.J Periodontol. 2006 Jul;77(7):1242-52. doi: 10.1902/jop.2006.050147. J Periodontol. 2006. PMID: 16805689
-
The effect of enamel matrix proteins on periodontal regeneration as determined by histological analyses.J Periodontol. 2003 Jul;74(7):1043-55. doi: 10.1902/jop.2003.74.7.1043. J Periodontol. 2003. PMID: 12931768
-
[Periodontitis and tissue regeneration].Nihon Hotetsu Shika Gakkai Zasshi. 2005 Aug;49(4):587-92. doi: 10.2186/jjps.49.587. Nihon Hotetsu Shika Gakkai Zasshi. 2005. PMID: 16121021 Review. Japanese.
-
Periodontal regeneration with a combination of enamel matrix proteins and autogenous bone grafting.J Periodontol. 2003 Sep;74(9):1269-81. doi: 10.1902/jop.2003.74.9.1269. J Periodontol. 2003. PMID: 14584859
-
Periodontal regeneration - intrabony defects: a consensus report from the AAP Regeneration Workshop.J Periodontol. 2015 Feb;86(2 Suppl):S105-7. doi: 10.1902/jop.2015.140378. Epub 2014 Oct 15. J Periodontol. 2015. PMID: 25315019
Cited by
-
Molecular Changes Underlying Hypertrophic Scarring Following Burns Involve Specific Deregulations at All Wound Healing Stages (Inflammation, Proliferation and Maturation).Int J Mol Sci. 2021 Jan 18;22(2):897. doi: 10.3390/ijms22020897. Int J Mol Sci. 2021. PMID: 33477421 Free PMC article. Review.
References
-
- Lekic P, Rojas J, Birek C, Tenenbaum H, McCulloch CA. Phenotypic comparison of periodontal ligament cells in vivo and in vitro. J Periodontal Res. 2001;36:71–9. - PubMed
-
- Seo BM, Miura M, Gronthos S, Bartold PM, Batouli S, Brahim J, et al. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet. 2004;364:149–55. - PubMed
-
- Gospodarowicz D. Localisation of a fibroblast growth factor and its effect alone and with hydrocortisone on 3T3 cell growth. Nature. 1974;249:123–7. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources