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Case Reports
. 2014 May;18(3):399-402.
doi: 10.4103/0972-124X.134591.

Platelet-rich fibrin as an adjunct to palatal wound healing after harvesting a free gingival graft: A case series

Mihir Raghavendra Kulkarni  1 , Betsy Sara Thomas  1 , Jothi M Varghese  1 , Giliyar Subraya Bhat  2
Affiliations
Case Reports

Platelet-rich fibrin as an adjunct to palatal wound healing after harvesting a free gingival graft: A case series

Mihir Raghavendra Kulkarni et al. J Indian Soc Periodontol. 2014 May.

Abstract

Background: Owing to its stimulatory effect on angiogenesis and epithelialization, platelet-rich fibrin (PRF) is an excellent material for enhancing wound healing. The use of PRF dressings may be a simple and effective method of reducing the morbidity associated with donor sites of autogenous free gingival grafts (FGGs). The purpose of this case series is to document the beneficial role of PRF in the healing of FGG donor sites.

Materials and methods: A total of 18 patients treated with FGGs could be classified into two groups. PRF was prepared, compressed and used to dress the palatal wound followed by a periodontal pack in one group (10 patients) and only a periodontal pack was used in the other group (8 patients). Post-operative healing was assessed clinically at 7, 14 and 21 days and the morbidity was assessed qualitatively by an interview.

Results: Sites where PRF was used showed complete wound closure by 14 days and these patients reported lesser post-operative morbidity than patients in whom PRF was not used.

Conclusions: PRF as a dressing is an effective method of enhancing the healing of the palatal donor site and consequently reducing the post-operative morbidity.

Keywords: Free gingival graft; healing; patient morbidity; platelet-rich fibrin; post-operative bleeding.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Free gingival graft harvested from the palate
Figure 2
Figure 2
Platelet-rich fibrin membrane
Figure 3
Figure 3
Platelet-rich fibrin membrane placed at the free gingival grafts donor site
Figure 4
Figure 4
Platelet-rich fibrin membrane secured to the palate
Figure 5
Figure 5
Donor site at 1 week post-operatively
Figure 6
Figure 6
Donor site at 2 weeks post-operatively
Figure 7
Figure 7
Healing of a site where platelet-rich fibrin was not used at 1 week post-operatively
Figure 8
Figure 8
Healing of a site where platelet-rich fibrin was not used at 2 weeks post-operatively
See this image and copyright information in PMC

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