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Comment
. 2014 Aug;15(8):498-9.
doi: 10.1038/nrm3843. Epub 2014 Jul 16.

Apoptosis. DR5 unfolds ER stress

Eytan Zlotorynski
Comment

Apoptosis. DR5 unfolds ER stress

Eytan Zlotorynski. Nat Rev Mol Cell Biol. 2014 Aug.

Abstract

ER stress induces apoptosis through DR5, which is regulated by the UPR factors PERK and IRE1α.

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References

    1. Nat Rev Mol Cell Biol. 2012 Jan 18;13(2):89-102 - PubMed
    1. Science. 2014 Jul 4;345(6192):98-101 - PubMed

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