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Comment
. 2014 Aug;134(8):2068-2069.
doi: 10.1038/jid.2014.172.

The thinning top: why old people have less hair

Sashank K Reddy  1 , Luis A Garza  2
Affiliations
Comment

The thinning top: why old people have less hair

Sashank K Reddy et al. J Invest Dermatol. 2014 Aug.

Abstract

Changes in the hair cycle underlie age-related alopecia, but the causative mechanisms have remained unclear. Chen et al. point to an imbalance between stem cell-activating and -inhibitory signals as the key determinant of age-related regenerative decline. Further, they identify a secreted protein, follistatin, that may be able to shift the balance toward renewal.

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References

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