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Case Reports
. 2014 May 15;7(6):3332-7.
eCollection 2014.

Small cell carcinoma of the endometrium: a case report with emphasis on the cytological features

Mitsuaki Ishida  1 , Nozomi Iwamoto  1 , Tetsuya Nakagawa  2 , Shouji Kaku  2 , Muneo Iwai  1 , Akiko Kagotani  1 , Kentarou Takahashi  3 , Takashi Murakami  2 , Hidetoshi Okabe  1
Affiliations
Case Reports

Small cell carcinoma of the endometrium: a case report with emphasis on the cytological features

Mitsuaki Ishida et al. Int J Clin Exp Pathol. .
No abstract available

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Figures

Figure 1
Figure 1
Cytological features of the endometrium. (A) Single or small clusters of neoplastic cells in a necrotic background. Papanicolaou staining, x 40. (B, C) The neoplastic cells have scant cytoplasm, and round to oval nuclei containing coarse chromatin and inconspicuous nucleoli. Nuclear molding is characteristic. Mitotic figures are present (arrow, C). Papanicolaou staining, x 400.
Figure 2
Figure 2
Histopathological and immunohistochemical features of the uterus tumor. A. Proliferation of small round cells with necrosis invading into the muscular layer of the uterus. HE, x 40. B. The neoplastic cells have scant cytoplasm, and round to oval nuclei containing coarse chromatin and inconspicuous nucleoli. HE, x 400. C. An endometrioid adenocarcinoma component is present adjacent to the small cell carcinoma in the surface of the endometrium. HE, x 40. D. The adenocarcinoma has large round to oval nuclei. HE, x 200. E. Synaptophysin is diffusely expressed in the small cell carcinoma component. x 400. F. Chromogranin A is also expressed in the small cell carcinoma component. A few chromogranin A-positive cells are present in the adenocarcinoma (inset). x 400.
Figure 3
Figure 3
Cytological features of the ascites. A. Single or small clusters of the neoplastic cells are observed. Papanicolaou staining, x 40. B. The neoplastic cells have scant cytoplasm and round to oval nuclei containing coarse chromatin and inconspicuous nucleoli. Nuclear molding is characteristic. Papanicolaou staining, x 400.
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References

    1. Abeler VM, Kjorstad KE, Nesland JM. Undifferentiated carcinoma of the endometrium: a histopathologic and clinical study of 31 cases. Cancer. 1991;68:98–105. - PubMed
    1. Ureyen I, Karalok A, Turan T, Boran N, Tapisiz OL, Okten H, Kose MF, Tulunay G. Small cell carcinoma of the endometrium: a report of three cases. J Turk Ger Gynecol Assoc. 2013;14:113–115. - PMC - PubMed
    1. Abaid LN, Cupp JS, Brown JV 3rd, Goldstein BH. Primary small cell neuroendocrine carcinoma of the endometrium. Case Rep Oncol. 2012;5:439–443. - PMC - PubMed
    1. Kurtay G, Taskin S, Kadan E, Sertcelik A. Primary endometrial small cell carcinoma. J Obstet Gynaecol. 2012;32:104–106. - PubMed
    1. Matsumoto H, Takai N, Nasu K, Narahara H. Small cell carcinoma of the endometrium: a report of two cases. J Obstet Gynaecol Res. 2011;11:1739–1743. - PubMed

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