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Review
. 2014 Aug;40(3):455-74, viii.
doi: 10.1016/j.rdc.2014.04.006.

The immunopathology of cutaneous lupus erythematosus

Mark G Kirchhof  1 , Jan P Dutz  2
Affiliations
Review

The immunopathology of cutaneous lupus erythematosus

Mark G Kirchhof et al. Rheum Dis Clin North Am. 2014 Aug.

Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the development of autoantibodies and immunologic attack of different organ systems, including the skin. This review aims to provide an overview of some of the pathogenic processes that may be important in the development of SLE, specifically cutaneous lupus erythematosus, and then illustrates how therapies might be tailored to modify these processes and treat disease.

Keywords: Chemokine; Cutaneous lupus erythematosus; Cytokine; Discoid lupus erythematosus; Interferon-α.

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