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Review
. 2014 Aug;40(3):475-95, viii.
doi: 10.1016/j.rdc.2014.04.003. Epub 2014 Jun 10.

Pathogenesis and treatment of atherosclerosis in lupus

Affiliations
Review

Pathogenesis and treatment of atherosclerosis in lupus

Maureen McMahon et al. Rheum Dis Clin North Am. 2014 Aug.

Abstract

The prevalence of atherosclerosis (ATH) is higher in patients with systemic lupus erythematosus (SLE) and occurs at an earlier age. The lupus-related factors that account for this increased risk are likely numerous and related to the factors described in this article. Identifying of at-risk subjects and increasing the understanding of pathogenesis of ATH in SLE is critical for improving the quality of care and improving mortality in this vulnerable population.

Keywords: Atherosclerosis; Cardiovascular diseases; Cytokine; Proinflammatory lipids; Systemic lupus erythematosus.

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