Pathogenesis and treatment of atherosclerosis in lupus
- PMID: 25034157
- PMCID: PMC6152881
- DOI: 10.1016/j.rdc.2014.04.003
Pathogenesis and treatment of atherosclerosis in lupus
Abstract
The prevalence of atherosclerosis (ATH) is higher in patients with systemic lupus erythematosus (SLE) and occurs at an earlier age. The lupus-related factors that account for this increased risk are likely numerous and related to the factors described in this article. Identifying of at-risk subjects and increasing the understanding of pathogenesis of ATH in SLE is critical for improving the quality of care and improving mortality in this vulnerable population.
Keywords: Atherosclerosis; Cardiovascular diseases; Cytokine; Proinflammatory lipids; Systemic lupus erythematosus.
Copyright © 2014 Elsevier Inc. All rights reserved.
References
-
- Urowitz MB, et al., The bimodal mortality pattern of systemic lupus erythematosus. Am J Med, 1976. 60(2): p. 221–5. - PubMed
-
- Abu-Shakra M, et al., Mortality studies in systemic lupus erythematosus. Results from a single center. II. Predictor variables for mortality. J Rheumatol, 1995. 22(7): p. 1265–70. - PubMed
-
- Schoenfeld SR, Kasturi S, and Costenbader KH, The epidemiology of atherosclerotic cardiovascular disease among patients with SLE: a systematic review. Semin Arthritis Rheum, 2013. 43(1): p. 77–95. - PubMed
-
- Manzi S, et al., Age-specific incidence rates of myocardial infarction and angina in women with systemic lupus erythematosus: comparison with the Framingham Study. Am J Epidemiol, 1997. 145(5): p. 408–15. - PubMed
-
- Shah MA, Shah AM, and Krishnan E, Poor outcomes after acute myocardial infarction in systemic lupus erythematosus. J Rheumatol, 2009. 36(3): p. 570–5. - PubMed
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