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Comment
. 2014 Jul 17;41(1):7-9.
doi: 10.1016/j.immuni.2014.07.003.

Memory T cells officially join the stem cell club

Luca Gattinoni  1
Affiliations
Comment

Memory T cells officially join the stem cell club

Luca Gattinoni. Immunity. .

Abstract

In this issue of Immunity, Graef et al. (2014) demonstrate self-renewal and multipotency of a single CD62L(+) memory T cell across serial adoptive transfers and infection-driven re-expansions, providing evidence of true stemness within the T cell memory compartment.

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Conflict of interest statement

Conflict-of-interest disclosure: The author declares no competing financial interests.

Figures

Figure 1:
Figure 1:. TCM cells function as adult stem cells.
Self-renewal and multipotency of a single central memory T cell (TCM) across serial adoptive transfers and infection-driven re-expansions ensure full immunocompetence. TN, naïve T cell; TEM, effector memory T cell; TEFF, effector T cell.
See this image and copyright information in PMC

Comment on

References

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