Tfr cells and IgA join forces to diversify the microbiota
- PMID: 25035948
- DOI: 10.1016/j.immuni.2014.06.012
Tfr cells and IgA join forces to diversify the microbiota
Abstract
How diversity of the microbiota is generated and maintained is an open question. In this issue of Immunity, Kawamoto et al. show that T follicular regulatory cells foster microbiota diversity via the regulation of IgA selection.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Foxp3(+) T cells regulate immunoglobulin a selection and facilitate diversification of bacterial species responsible for immune homeostasis.Immunity. 2014 Jul 17;41(1):152-65. doi: 10.1016/j.immuni.2014.05.016. Epub 2014 Jul 10. Immunity. 2014. PMID: 25017466
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