Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1989 Jun;9(6):2752-5.
doi: 10.1128/mcb.9.6.2752-2755.1989.

Regulation of tissue factor gene expression in the monocyte procoagulant response to endotoxin

S A Gregory  1 , J H Morrissey, T S Edgington
Affiliations

Regulation of tissue factor gene expression in the monocyte procoagulant response to endotoxin

S A Gregory et al. Mol Cell Biol. 1989 Jun.

Abstract

Tissue factor is the cellular receptor and cofactor for plasma factor VIIa which initiates the coagulation protease cascade on cell surfaces. Although normally absent from all intravascular cell types, tissue factor can be induced to appear on circulating monocytes and vascular endothelial cells by specific inflammatory or immunological mediators. In this study, we have examined the regulation of endotoxin-induced tissue factor gene expression in peripheral blood monocytes.

PubMed Disclaimer

References

    1. J Clin Invest. 1983 Jun;71(6):1893-6 - PubMed
    1. J Exp Med. 1984 Aug 1;160(2):618-23 - PubMed
    1. J Clin Invest. 1978 Sep;62(3):649-55 - PubMed
    1. J Immunol. 1988 Sep 15;141(6):2006-15 - PubMed
    1. Blood. 1977 Jun;49(6):947-56 - PubMed

Publication types

LinkOut - more resources