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Review
. 2014 Jul 18:12:227.
doi: 10.1186/1477-7819-12-227.

Testicular desmoplastic small round cell tumor: a case report and review of literature

Gui-Ming Zhang, Yao Zhu, Hua-Lei Gan, Ding-Wei Ye  1
Affiliations
Review

Testicular desmoplastic small round cell tumor: a case report and review of literature

Gui-Ming Zhang et al. World J Surg Oncol. .

Abstract

Background: Desmoplastic small round cell tumor (DSRCT) is an uncommon and highly aggressive malignancy with undetermined histogenesis and poor prognosis. To date, no case of testicular DSRCT has been reported in the literature.

Case: A 42-year-old Chinese man presented with painless swelling of his left testis and a painless palpable nodule in his left inguinal region. Computed tomography showed a solid mass in the left testis and multiple metastases in the body. Laboratory tests gave no abnormal results. Left radical orchiectomy was performed, and histopathological and molecular pathological examination showed typical features of DSRCT. Six cycles of chemotherapy were administrated after the operation, leading to partial remission. Postoperative 9-month follow-up indicated no progression.

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Figures

Figure 1
Figure 1
Computed tomography showed multiple lesions in left inguinal region, and near-bilateral iliac vessels, suggestive of multiple metastases.
Figure 2
Figure 2
Well-defined nests of small round blue cells separated by abundant desmoplastic stroma (hematoxylin and eosin stain; magnification × 100).
Figure 3
Figure 3
Desmin was positive for immunohistochemistry. Magnification × 200.
Figure 4
Figure 4
Computed tomography showed shrunken lesions in left inguinal region, and near-bilateral iliac vessels in the ninth postoperative month.
See this image and copyright information in PMC

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