Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014 Nov;107(4):428-30.
doi: 10.1111/vox.12177. Epub 2014 Jul 16.

Microchimerism in the transfused obstetric population

E M Bloch  1 , M P Busch, T-H Lee, L Montalvo, Y Matthews, A Bird, R Bruhn, V Stefan
Affiliations

Microchimerism in the transfused obstetric population

E M Bloch et al. Vox Sang. 2014 Nov.

Abstract

Microchimerism (MC), the coexistence of allogeneic populations of cells within a host, is well described in pregnancy and blood transfusion. To date, transfusion-associated MC (TA-MC) appears unique to patients transfused after severe traumatic injury. We sought to determine whether transfusion in the peripartum period results in enduring, high-level TA-MC. We conducted a prospective cohort study of 22 women who were newly transfused within 48 h of delivery. Two subjects showed evidence of transient TA-MC; however, MC was not detected at 6 weeks and 6 months. The negative findings suggest that enduring TA-MC does not occur in this population.

Keywords: blood transfusion; chimerism; peripartum.

PubMed Disclaimer

Publication types

LinkOut - more resources