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Clinical Trial
. 1989 Aug;32(8):964-73.
doi: 10.1002/anr.1780320805.

Double-blind trial of recombinant gamma-interferon versus placebo in the treatment of rheumatoid arthritis

G W Cannon  1 , S H Pincus, R D Emkey, A Denes, S A Cohen, F Wolfe, P A Saway, A M Jaffer, A L Weaver, L Cogen, et al.
Affiliations
Clinical Trial

Double-blind trial of recombinant gamma-interferon versus placebo in the treatment of rheumatoid arthritis

G W Cannon et al. Arthritis Rheum. 1989 Aug.

Abstract

One hundred five patients were enrolled in a 12-week, randomized, prospective, double-blind, placebo-controlled trial of recombinant human gamma-interferon (rHu gamma-IFN) for the treatment of rheumatoid arthritis. Fifty-four patients received rHu gamma-IFN and 51 received placebo. Forty-two patients in each group completed the 12-week trial. Some clinical improvement occurred in both groups of patients. Although the improvement with rHu gamma-IFN was greater than that with placebo, the differences were generally not statistically significant.

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