Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Jun 27;18(3):159.
doi: 10.1186/cc13950.

Tight glycemic control in the ICU - is the earth flat?

Garry M Steil, Michael S D Agus
Comment

Tight glycemic control in the ICU - is the earth flat?

Garry M Steil et al. Crit Care. .

Abstract

Tight glycemic control in the ICU has been shown to reduce mortality in some but not all prospective randomized control trials. Confounding the interpretation of these studies are differences in how the control was achieved and underlying incidence of hypoglycemia, which can be expected to be affected by the introduction of continuous glucose monitoring (CGM). In this issue of Critical Care, a consensus panel provides a list of the research priorities they believe are needed for CGM to become routine practice in the ICU. We reflect on these recommendations and consider the implications for using CGM today.

PubMed Disclaimer

Comment on

  • Continuous glucose control in the ICU: report of a 2013 round table meeting.
    Wernerman J, Desaive T, Finfer S, Foubert L, Furnary A, Holzinger U, Hovorka R, Joseph J, Kosiborod M, Krinsley J, Mesotten D, Nasraway S, Rooyackers O, Schultz MJ, Van Herpe T, Vigersky RA, Preiser JC. Wernerman J, et al. Crit Care. 2014 Jun 13;18(3):226. doi: 10.1186/cc13921. Crit Care. 2014. PMID: 25041718 Free PMC article. Review.

References

    1. Wernerman J, Desaive D, Finfer S, Foubert L, Furnary A, Holzinger U, Hovorka R, Joseph J, Kosiborod M, Krinsley J, Mesotten D, Nasraway S, Rooyackers O, Schulz MJ, Van Herpe T, Vigersky RA, Preiser J-C. Continuous glucose control in the ICU: report of a 2013 Round Table meeting. Crit Care. 2014;18:226. doi: 10.1186/cc13921. - DOI - PMC - PubMed
    1. Agus MS, Steil GM, Wypij D, Costello JM, Laussen PC, Langer M, Alexander JL, Scoppettuolo LA, Pigula FA, Charpie JR, Ohye RG. Gaies MG; SPECS Study Investigators: Tight glycemic control versus standard care after pediatric cardiac surgery. N Engl J Med. 2012;367:1208–1219. doi: 10.1056/NEJMoa1206044. - DOI - PMC - PubMed
    1. Krinsley JS, Egi M, Kiss A, Devendra AN, Schuetz P, Maurer PM, Schultz MJ, van Hooijdonk RT, Kiyoshi M, Mackenzie IM, Annane D, Stow P, Nasraway SA, Holewinski S, Holzinger U, Preiser JC, Vincent JL, Bellomo R. Diabetic status and the relation of the three domains of glycemic control to mortality in critically ill patients: an international multicenter cohort study. Crit Care. 2013;17:R37. doi: 10.1186/cc12547. - DOI - PMC - PubMed
    1. Wilson M, Weinreb J, Hoo GW. Intensive insulin therapy in critical care: a review of 12 protocols. Diabetes Care. 2007;30:1005–1011. doi: 10.2337/dc06-1964. - DOI - PubMed
    1. Steil GM, Deiss D, Shih J, Buckingham B, Weinzimer S, Agus MS. Intensive care unit insulin delivery algorithms: Why so many? How to choose? J Diabetes Sci Technol. 2009;3:125–140. doi: 10.1177/193229680900300114. - DOI - PMC - PubMed

Publication types