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. 1989 Jun;217(2-3):520-7.
doi: 10.1007/BF02464926.

The genetics of position-effect variegation modifying loci in Drosophila melanogaster

G Wustmann  1 , J Szidonya, H Taubert, G Reuter
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The genetics of position-effect variegation modifying loci in Drosophila melanogaster

G Wustmann et al. Mol Gen Genet. 1989 Jun.

Abstract

The dose dependent effects of position-effect variegation (PEV) modifying genes were studied in chromosome arms 2L, 2R and 3R. Four groups of PEV modifying genes can be distinguished: haplo-abnormal suppressor and enhancer loci with or without a triplo-effect. Using duplications four triplo-abnormal suppressor and four triplo-abnormal enhancer functions were localized. In two cases we proved that these functions correspond to a converse haplo-abnormal one. Altogether 43 modifier loci were identified. Most of these loci proved not to display significant triplo-effects (35). The group of haplo-abnormal loci with a triplo-effect may represent genes which play an important role in heterochromatin packaging.

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