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Review
. 2014 Jun;10(8):1427-41.
doi: 10.2217/fon.14.23.

Cancers of the anal canal: diagnosis, treatment and future strategies

Emma Bown  1 , Vikas Shah, Thiagarajan Sridhar, Kirsten Boyle, David Hemingway, Justin M Yeung
Affiliations
Review

Cancers of the anal canal: diagnosis, treatment and future strategies

Emma Bown et al. Future Oncol. 2014 Jun.

Abstract

Anal cancer is an uncommon cancer; however, it is rising in incidence. There is confusion regarding nomenclature and the distinction between anal canal cancer and anal margin cancer. This article discusses the modern definition, etiology and staging of anal canal and anal margin cancers. Modern chemotherapy and radiotherapy regimens are discussed, in addition to modern imaging and radiotherapy techniques. Future preventative strategies and potential novel treatments are discussed.

Keywords: anal canal cancer; anal margin cancer; human papillomavirus; salvage APER.

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