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We sequenced the complete genome of the widely used C57L/J mouse inbred strain. With 40× average coverage, we compared the C57L/J sequence with that of the C57BL/6J and identified many known as well as novel private variants. This genome sequence adds another strain to the growing number of mouse inbred strains with complete genome sequences and is a valuable resource to the scientific community.
Aljakna A., Choi S., Savage H., Hageman Blair R., Gu T., et al. , 2012. Pla2g12b and Hpn are genes identified by mouse ENU mutagenesis that affect HDL cholesterol. PLoS ONE 7: e43139.
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PMC
-
PubMed
Calpena E., Casado M., Martínez-Rubio D., Nascimento A., Colomer J., et al. , 2013. 5-Oxoprolinuria in heterozygous patients for 5-oxoprolinase (OPLAH) missense changes. JIMD Rep 7: 123–128
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PMC
-
PubMed
Chen K., Wallis J. W., McLellan M. D., Larson D. E., Kalicki J. M., et al. , 2009. BreakDancer: an algorithm for high-resolution mapping of genomic structural variation. Nat. Methods 6: 677–681
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PubMed
Cingolani P., Platts A., Wang L. L., Coon M., Nguyen T., et al. , 2012. A program for annotating and predicting the effects of single nucleotide polymorphisms, SnpEff: SNPs in the genome of Drosophila melanogaster strain w1118; iso-2; iso-3. Fly (Austin) 6: 80–92
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DePristo M. A., Banks E., Poplin R., Garimella K. V., Maguire J. R., et al. , 2011. A framework for variation discovery and genotyping using next-generation DNA sequencing data. Nat. Genet. 43: 491–498
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PMC
-
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