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. 2014 May-Jun;54(3):247-9.

When anti-TNF fails, anti-IL12-23 is an alternate option in psoriasis and psoriatic arthritis

[Article in English, Portuguese]
Ricardo Prado Golmia, Ayk Helena Barbosa Martins, Morton Scheinberg
  • PMID: 25054605
Free article

When anti-TNF fails, anti-IL12-23 is an alternate option in psoriasis and psoriatic arthritis

[Article in English, Portuguese]
Ricardo Prado Golmia et al. Rev Bras Reumatol. 2014 May-Jun.
Free article

Abstract

Patients with psoriasis and psoriatic arthritis respond to anti-TNF therapy, but not all patients maintain effective response, and some do not respond. In this article, we demonstrate the role of a new pathogenetic pathway to some extent TNF-independent in these patients. Anti-IL12-23 is a new and alternate mode of therapy for patients with recalcitrant response to anti-TNF.

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