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1 Department of Bacteriology, Nice Academic Hospital, Nice, France Nice Medical University, Nice-Sophia Antipolis University, Nice, France lotte.r@chu-nice.fr.
2 Centre de Référence des Bactéries Anaérobies et du Botulisme, Pasteur Institute, Paris, France.
3 Department of Bacteriology, Nice Academic Hospital, Nice, France.
4 Department of Radiology, Nice Academic Hospital, Nice, France.
5 Department of Infectious Diseases, Nice Academic Hospital, Nice, France.
6 Nice Medical University, Nice-Sophia Antipolis University, Nice, France Department of Infectious Diseases, Nice Academic Hospital, Nice, France.
7 Department of Bacteriology, Nice Academic Hospital, Nice, France Nice Medical University, Nice-Sophia Antipolis University, Nice, France.
1 Department of Bacteriology, Nice Academic Hospital, Nice, France Nice Medical University, Nice-Sophia Antipolis University, Nice, France lotte.r@chu-nice.fr.
2 Centre de Référence des Bactéries Anaérobies et du Botulisme, Pasteur Institute, Paris, France.
3 Department of Bacteriology, Nice Academic Hospital, Nice, France.
4 Department of Radiology, Nice Academic Hospital, Nice, France.
5 Department of Infectious Diseases, Nice Academic Hospital, Nice, France.
6 Nice Medical University, Nice-Sophia Antipolis University, Nice, France Department of Infectious Diseases, Nice Academic Hospital, Nice, France.
7 Department of Bacteriology, Nice Academic Hospital, Nice, France Nice Medical University, Nice-Sophia Antipolis University, Nice, France.
We report here a rare case of chronic lumbar discitis caused by Clostridium perfringens in an elderly patient that was treated with a combination of β-lactams and clindamycin. Molecular analysis performed on the strain revealed an unusual toxin gene pattern.
Computed tomography images of an axial section of a soft-tissue window on the…
FIG 1
Computed tomography images of an axial section of a soft-tissue window on the L4-L5 disk (A) and a sagittal section of a bone window (B) are shown. A large central gas bubble (white star), erosions of the endplates (thin arrows), and fluid collection with a gas bubble in the left paraspinal soft tissues (wide arrow) are indicated.
Clinical and Laboratory Standards Institute. 2012. Methods for antimicrobial susceptibility testing of anaerobic bacteria, vol 27, no 2 Approved standard, 8th ed, M11-A8 CLSI, Wayne, PA
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Société de Pathologie Infectieuse de Langue Française. 2007. Spondylodiscites: recommandations pour la pratique clinique. Société de Pathologie Infectieuse de Langue Française, Grenoble, France
Bednar DA. 2002. Postoperative Clostridium perfringens lumbar discitis with septicemia: report of a case with survival. J. Spinal Disord. Tech. 15:172–174. 10.1097/00024720-200204000-00014
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Caudron A, Grados F, Boubrit Y, Coullet JM, Merrien D, Domart Y. 2008. Discitis due to Clostridium perfringens. Joint Bone Spine 75:232–234. 10.1016/j.jbspin.2007.04.026
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Pate D, Katz A. 1979. Clostridia discitis: a case report. Arthritis Rheum. 22:1039–1040. 10.1002/art.1780220916
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