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Comment
. 2014 Aug;63(8):2609-10.
doi: 10.2337/db14-0609.

Metformin pharmacogenomics: biomarkers to mechanisms

Liewei Wang  1 , Richard Weinshilboum  2
Affiliations
Comment

Metformin pharmacogenomics: biomarkers to mechanisms

Liewei Wang et al. Diabetes. 2014 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Schematic representation of the cellular locations of SLC transporters that contribute to metformin pharmacokinetics. It has been reported that the genes encoding SLC22A1, MATE1, and MATE2 are genetically polymorphic and that these polymorphisms contribute to individual variation in metformin pharmacokinetics (–9). SLC22A1 = OCT1, SLC22A2 = OCT2, SLC22A3 = OCT3, SLC29A4 = ENT4, SLC47A1 = MATE1, and SLC47A2 = MATE2.
See this image and copyright information in PMC

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References

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