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Comment
. 2014 Sep;45(9):e177-8.
doi: 10.1161/STROKEAHA.114.005640. Epub 2014 Jul 24.

Modeling immunity and inflammation in stroke: can mice be trusted?

Ulrich Dirnagl  1
Affiliations
Comment

Modeling immunity and inflammation in stroke: can mice be trusted?

Ulrich Dirnagl. Stroke. 2014 Sep.
No abstract available

Keywords: immune system; inflammation; models, animal; stroke.

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  • Genomic responses in mouse models poorly mimic human inflammatory diseases.
    Seok J, Warren HS, Cuenca AG, Mindrinos MN, Baker HV, Xu W, Richards DR, McDonald-Smith GP, Gao H, Hennessy L, Finnerty CC, López CM, Honari S, Moore EE, Minei JP, Cuschieri J, Bankey PE, Johnson JL, Sperry J, Nathens AB, Billiar TR, West MA, Jeschke MG, Klein MB, Gamelli RL, Gibran NS, Brownstein BH, Miller-Graziano C, Calvano SE, Mason PH, Cobb JP, Rahme LG, Lowry SF, Maier RV, Moldawer LL, Herndon DN, Davis RW, Xiao W, Tompkins RG; Inflammation and Host Response to Injury, Large Scale Collaborative Research Program. Seok J, et al. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3507-12. doi: 10.1073/pnas.1222878110. Epub 2013 Feb 11. Proc Natl Acad Sci U S A. 2013. PMID: 23401516 Free PMC article. Clinical Trial.

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