Developing microphysiological systems for use as regulatory tools--challenges and opportunities
- PMID: 25061900
- PMCID: PMC4778746
- DOI: 10.14573/altex.1405151
Developing microphysiological systems for use as regulatory tools--challenges and opportunities
References
-
- Arrowsmith J. Trial watch: Phase II failures: 2008–2010. Nat Rev Drug Discov. 2011;10:328–329. http://dx.doi.org/10.1038/nrd3439. - DOI - PubMed
-
- Huh D, Matthews BD, Mammoto A, et al. Reconstituting organ-level lung functions on a chip. Science. 2010;328:1662–1668. http://dx.doi.org/10.1126/science.1188302. - DOI - PMC - PubMed
-
- Huh D, Leslie DC, Matthews BD, et al. A human disease model of drug toxicity – induced pulmonary edema in a lung-on-a-chip microdevice. Sci Trans Med. 2012;4:159ra147. http://dx.doi.org/10.1126/scitranslmed.3004249. - DOI - PMC - PubMed
-
- Kim HJ, Huh D, Hamilton G, Ingber DE. Human gut-on-a-chip inhabited by microbial flora that experiences intestinal peristalsis-like motions and flow. Lab Chip. 2012;12:2165–2174. http://dx.doi.org/10.1039/C2LC40074J. - DOI - PubMed
-
- Kim HJ, Ingber DE. Gut-on-a-Chip microenvironment induces human intestinal cells to undergo villus differentiation. Integr Biol (Camb) 2013;5:1130–1140. http://dx.doi.org/10.1039/c3ib40126j. - DOI - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
