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. 2014 Nov;29(7):670-9.
doi: 10.1093/arclin/acu031. Epub 2014 Jul 25.

The free and cued selective reminding test distinguishes frontotemporal dementia from Alzheimer's disease

Raquel Lemos  1 , Diana Duro  2 , Mário R Simões  3 , Isabel Santana  2
Affiliations

The free and cued selective reminding test distinguishes frontotemporal dementia from Alzheimer's disease

Raquel Lemos et al. Arch Clin Neuropsychol. 2014 Nov.

Abstract

Memory impairment is often present in frontotemporal dementia (FTD) as a result of an inefficient use of learning strategies, sometimes leading to a misdiagnosis of Alzheimer's disease (AD). The Free and Cued Selective Reminding Test (FCSRT) is a memory test that controls attention and acquisition, by providing category cues in the learning process. The main goal of this study was to show the usefulness of the FCSRT in the distinction between behavioral (bv-) FTD and AD. Three matched subgroups of participants were considered: bv-FTD (n = 32), AD (n = 32), and a control group of healthy adults (n = 32). Results proved that while AD patients exhibited an overall impairment in FCSRT, bv-FTD subjects showed to benefit more from the controlled learning through category cues. AD patients were 25 times more likely to have an impaired FCSRT. The FCSRT has shown its utility in the distinction between bv-FTD and AD, therefore increasing the diagnostic accuracy.

Keywords: Alzheimer's disease; Assessment; Frontotemporal dementia; Learning and memory.

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Figures

Fig. 1.
Fig. 1.
Free, cued, and total recalls (mean) in the FCSRT along the first, second, and third learning trials. bv-FTD = behavioral frontotemporal dementia; AD = Alzheimer's disease.
See this image and copyright information in PMC

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