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. 2014 Sep 1;53(36):9426-8.
doi: 10.1002/anie.201405714. Epub 2014 Jul 27.

Functionalization of remote C-H bonds: expanding the frontier

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Functionalization of remote C-H bonds: expanding the frontier

Johannes Schranck et al. Angew Chem Int Ed Engl. .

Abstract

Novel tool set: New methodologies for the functionalization of remote CH bonds have been developed recently. In diverse approaches high selectivities are achieved for the functionalization of less reactive C(sp(2) )H as well as C(sp(3) )H bonds distal to any substituents.

Keywords: C-H activation; arylation; directing groups; regioselectivity.

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