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. 2014 Sep;219(3):335-45.
doi: 10.1016/j.jamcollsurg.2014.04.011. Epub 2014 May 27.

Scudder Oration on Trauma. A century of evolution in trauma resuscitation

Ronald V Maier  1
Affiliations

Scudder Oration on Trauma. A century of evolution in trauma resuscitation

Ronald V Maier. J Am Coll Surg. 2014 Sep.
No abstract available

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Figures

Figure 1
Figure 1
Maier Surgical Family: (A) C James Carrico, MD; (B) Donald D Trunkey, MD; (C) David B Hoyt, MD; (D) Ernest E Moore, MD; (E) Gregory J. Jurkovich, MD; and (F) Carlos A Pellegrini, MD.
Figure 2
Figure 2
General Surgery, Trauma, Burns and Surgical Critical Care Faculty, Harborview Medical Center, University of Washington.
Figure 3
Figure 3
Maier Family: John Michael, Lauren, and Anna Maier.
Figure 4
Figure 4
Resuscitation volume proposals to reach euvolemia in traumatic shock: (A) biologic sine wave oscillating above and below the mean (euvolemia) goal; (B) chaos theory approach to complex systems biology of euvolemia.
Figure 5
Figure 5
Differences in gene expression patterns between patients with a complicated and uncomplicated clinical recovery. (A) Probe sets differentially expressed. Heat map of gene probe sets whose expression was at least twofold different when compared with controls (CTRL) for patients with a complicated (Comp) or uncomplicated recovery (Uncomp). (B) Mean expression over time. Mean gene probe expression changes vs time course of return to normal function (homeostasis) of significantly altered genes post injury. Upper panel are upregulated primarily proinflammatory innate immunity genes and lower portion are suppressed primarily adaptive immunity genes. Patients with complicated clinical courses have a delay in return toward normal. Recovery2: red, control; green, uncomplicated; blue, complicated. (Adapted with permission from Xiao et al., 2011. Originally published in The Journal of Experimental Medicine.)
Fig. 6
Fig. 6
Fluid resuscitation volume protocols for traumatic shock over time fulfill the chaos theory.
See this image and copyright information in PMC

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