[Heavy gamma-chain diseases. A new case and review of the literature]

Abstract

IgG heavy chain disease is a rare disorder in which incomplete monoclonal immunoglobulins are synthesized. We report herein a new case diagnosed in an 84 year old woman and present a review of the different descriptions available in the literature. This pathology often has an insidious onset. Its clinical and evolutive aspects are highly variable and linked to an associated disease, which has led us to emphasize the diagnostic difficulties and to discuss the nosology of this disorder.