Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014;78(11):1906-9.
doi: 10.1080/09168451.2014.940834. Epub 2014 Jul 29.

Manno-oligosaccharide-binding ability of mouse RegIV/GST-fusion protein evaluated by complex formation with the carbohydrate-containing polyamidoamine dendrimer

Yuta Kato  1 , Kazunori Kochi, Hideaki Unno, Shuichiro Goda, Tomomitsu Hatakeyama
Affiliations

Manno-oligosaccharide-binding ability of mouse RegIV/GST-fusion protein evaluated by complex formation with the carbohydrate-containing polyamidoamine dendrimer

Yuta Kato et al. Biosci Biotechnol Biochem. 2014.

Abstract

The carbohydrate-binding properties of the C-type lectin-like mouse RegIV and glutathione S-transferase-fusion protein (GST-mRegIV) were examined using carbohydrate-containing polyamidoamine dendrimers (PD). GST-mRegIV showed affinity for mannan- and manno-oligosaccharide containing PD. Binding was inhibited by manno-oligosaccharides but not by mannose or other tested carbohydrates, suggesting that the binding site may have an extended structure in contrast with typical C-type lectins.

Keywords: RegIV; binding; light scattering; mannose; polyamidoamine dendrimer.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

  • Soluble Human Lectins at the Host-Microbe Interface.
    Peiffer AL, Dugan AE, Kiessling LL. Peiffer AL, et al. Annu Rev Biochem. 2024 Aug;93(1):565-601. doi: 10.1146/annurev-biochem-062917-012322. Epub 2024 Jul 2. Annu Rev Biochem. 2024. PMID: 38640018 Free PMC article. Review.

Publication types

LinkOut - more resources