Soft tissue sarcomas

Abstract

Sarcoma is a cancer that arises from cells of mesenchymal origin, such as bone, cartilage, muscle, fat, vascular, or hematopoietic tissue. It is a very rare form of cancer with over 50 histologic subtypes. This chapter discusses selected individual subtypes of sarcomas and characteristics specific to each one. It will broadly go over molecular biology, etiology, risk factors, and the clinical features of this disease. It discusses diagnostic evaluation and the principles of management including imaging, biopsy, staging, treatment, follow-up, and the importance of a multidisciplinary approach.