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Comment
. 2014 Sep;11(9):504-5.
doi: 10.1038/nrcardio.2014.111. Epub 2014 Jul 29.

Atrial fibrillation. Cryptogenic stroke--can we abandon this apologetic diagnosis?

A John Camm  1
Affiliations
Comment

Atrial fibrillation. Cryptogenic stroke--can we abandon this apologetic diagnosis?

A John Camm. Nat Rev Cardiol. 2014 Sep.

Abstract

Cryptogenic stroke is an apology for ignorance about the cause of ischaemic stroke. Now, in two new studies involving long-term electrocardiogram monitoring, investigators from the EMBRACE and CRYSTAL-AF trials suggest that many instances of cryptogenic stroke might be caused by undetected atrial fibrillation.

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  • Atrial fibrillation in patients with cryptogenic stroke.
    Gladstone DJ, Spring M, Dorian P, Panzov V, Thorpe KE, Hall J, Vaid H, O'Donnell M, Laupacis A, Côté R, Sharma M, Blakely JA, Shuaib A, Hachinski V, Coutts SB, Sahlas DJ, Teal P, Yip S, Spence JD, Buck B, Verreault S, Casaubon LK, Penn A, Selchen D, Jin A, Howse D, Mehdiratta M, Boyle K, Aviv R, Kapral MK, Mamdani M; EMBRACE Investigators and Coordinators. Gladstone DJ, et al. N Engl J Med. 2014 Jun 26;370(26):2467-77. doi: 10.1056/NEJMoa1311376. N Engl J Med. 2014. PMID: 24963566 Clinical Trial.
  • Cryptogenic stroke and underlying atrial fibrillation.
    Sanna T, Diener HC, Passman RS, Di Lazzaro V, Bernstein RA, Morillo CA, Rymer MM, Thijs V, Rogers T, Beckers F, Lindborg K, Brachmann J; CRYSTAL AF Investigators. Sanna T, et al. N Engl J Med. 2014 Jun 26;370(26):2478-86. doi: 10.1056/NEJMoa1313600. N Engl J Med. 2014. PMID: 24963567 Clinical Trial.

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