Successful Treatment of Eccrine Porocarcinoma Metastasized to a Cervical Lymph Node with CyberKnife Radiosurgery

Abstract

Eccrine porocarcinoma is a rare type of skin cancer that originates from eccrine sweat glands or acrosyringium and mainly occurs in the elderly. In this report, we describe an 85-year-old Japanese woman with eccrine porocarcinoma that metastasized to a cervical lymph node who was cured with CyberKnife radiosurgery. Because our patient had a high risk of perioperative complication, standard surgical therapy with a wide margin was impractical. Our present study suggests the novel possibility of using CyberKnife for the treatment of inoperable metastatic porocarcinoma.

Keywords: CyberKnife; Eccrine porocarcinoma; Stereotactic radiotherapy.

Fig. 1

a A red, easy-to-bleed, dome-shaped nodule 20 mm in diameter on the right cheek. b Dermoscopy findings revealed irregular arborizing vessels and whitish globular structures covered by prominent bleeding.

Fig. 2

Dense infiltration of clear, cuboidal, basaloid atypical cells infiltrating throughout the dermis. Original magnification: ×50 (a), ×200 (b).

Fig. 3

a Positron emission tomography-computed tomography revealed significant enlargement of the cervical lymph nodes. b One month after the irradiation, follow-up computed tomography scan revealed that the tumor mass had completely regressed.