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Comment
. 2014 Aug;16(8):739-41.
doi: 10.1038/ncb3018.

A growing role for Aurora A in chromosome instability

Ana R R Maia  1 , Roy G H P van Heesbeen  1 , René H Medema  1
Affiliations
Comment

A growing role for Aurora A in chromosome instability

Ana R R Maia et al. Nat Cell Biol. 2014 Aug.

Abstract

Chromosome instability is a major hallmark of cancer, but its molecular causes are still poorly understood. A study now describes how genetic alterations frequently found in colorectal cancer increase microtubule assembly rates during mitosis and promote chromosome instability.

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