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. 2014 Aug 15;16(16):4280-3.
doi: 10.1021/ol5020015. Epub 2014 Aug 1.

Synthesis of silyl monoperoxyketals by regioselective cobalt-catalyzed peroxidation of silyl enol ethers: application to the synthesis of 1,2-dioxolanes

Brisa Hurlocker  1 , Matthew R Miner, K A Woerpel
Affiliations

Synthesis of silyl monoperoxyketals by regioselective cobalt-catalyzed peroxidation of silyl enol ethers: application to the synthesis of 1,2-dioxolanes

Brisa Hurlocker et al. Org Lett. .

Abstract

The cobalt-catalyzed peroxidation of silyl enol ethers with molecular oxygen and triethylsilane provided silyl monoperoxyketals in 54%-96% yield. These compounds serve as precursors to peroxycarbenium ions, which undergo annulations to provide 1,2-dioxolanes.

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