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Case Reports
. 2014 Dec;21(12):2249-51.
doi: 10.1016/j.jocn.2014.04.019. Epub 2014 Jul 29.

Audiological evidence of therapeutic effect of steroid treatment in neuromyelitis optica with hearing loss

Yoshitaka Takanashi  1 , Tatsuro Misu  2 , Kazuha Oda  3 , Hiromitsu Miyazaki  3 , Izumi Yahata  3 , Hiroshi Hidaka  3 , Kazuo Fujihara  2 , Tetsuaki Kawase  4 , Toshimitsu Kobayashi  3 , Yukio Katori  3
Affiliations
Case Reports

Audiological evidence of therapeutic effect of steroid treatment in neuromyelitis optica with hearing loss

Yoshitaka Takanashi et al. J Clin Neurosci. 2014 Dec.

Abstract

Neuromyelitis optica (NMO) is an autoimmune astrocytopathy caused by anti-aquaporin 4 antibody. Only two patients with NMO have been reported presenting with hearing disorders to our knowledge. We recently treated a 40-year-old woman with NMO complaining of right hearing loss. Audiometry showed minimal asymmetry, but the auditory brainstem responses (ABR) were severely attenuated on the right. The attenuated ABR and her aural symptoms (hearing loss and fullness) improved after steroid treatment. The present case shows that the retrocochlear-type hearing loss may be associated with NMO.

Keywords: Auditory brainstem response; Multiple sclerosis; Neuromyelitis optica.

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