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. 2014 Aug 1;592(15):3167-70.
doi: 10.1113/jphysiol.2014.271809.

CrossTalk opposing view: Rotors have not been demonstrated to be the drivers of atrial fibrillation

Maurits Allessie  1 , Natasja de Groot  2
Affiliations

CrossTalk opposing view: Rotors have not been demonstrated to be the drivers of atrial fibrillation

Maurits Allessie et al. J Physiol. .
No abstract available

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Figures

Figure 1
Figure 1
Endo-epicardial breakthroughs recorded by high-resolution mapping of acutely induced human AF A flexible rectangular array of 8 × 16 electrodes was positioned consecutively on different parts of the atria (10 s recordings). Breakthroughs occurred at multiple sites distributed over the entire epicardial surface of the left and right atrium. The diagram at the bottom illustrates how endo-epicardial breakthrough sites may serve as sources of ‘new’ fibrillation waves (modified from de Groot et al. 2010).
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References

    1. Allessie MA, Bonke FIM, Schopman FJG. Circus movement in rabbit atrial muscle as a mechanism of tachycardia. III. The ‘leading circle’ concept: a new model of circus movement in cardiac tissue without the involvement of an anatomic obstacle. Circ Res. 1977;41:9–18. - PubMed
    1. Allessie MA, de Groot NMS. Wave-mapping as a guide for ablation of atrial fibrillation: a daydream? Circ Arrhythm Electrophysiol. 2013;6:1056–1058. - PubMed
    1. Allessie MA, de Groot NMS. Rotors during AF: drivers or bystanders? Eur Heart J. 2014;35:63–65. - PubMed
    1. Allessie MA, de Groot NMS, Houben RPM, Schotten U, Boersma E, Smeets JL, Crijns HJ. Electropathological substrate of long-standing persistent atrial fibrillation in patients with structural heart disease: longitudinal dissociation. Circ Arrhythm Electrophysiol. 2010;3:606–615. - PubMed
    1. Allessie MA, Lammers WJEP, Bonke FIM. Experimental evaluation of Moe's multiple wavelet hypothesis of atrial fibrillation. In: Zipes DP, Jalife J, Hollen SJ, editors. Cardiac Arrhythmias. 1st edn. Grune & Stratton; 1985. pp. 265–276.

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