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. 2014 Aug 4;19(8):11453-64.
doi: 10.3390/molecules190811453.

An unusual piceatannol dimer from Rheum austral D. Don with antioxidant activity

Affiliations

An unusual piceatannol dimer from Rheum austral D. Don with antioxidant activity

Lin Hu et al. Molecules. .

Abstract

A novel dimer of piceatannol glycoside, named rheumaustralin (1) was isolated from the underground parts of the ethnomedicinal plant Rheum austral (Polygonaceae) collected from Tibet together with 17 known compounds, including rheumin (2), 2,5-dimethyl-7-hydroxychromone (3), 2,5-dimethylchromone-7-O-β-D-glucopyranoside (4), 7-hydroxy-2-(2'-hydroxypropyl)-5-methylchromone (5), torachrysone (6) torachrysone-8-O-β-D-glucopyranoside (7), 4-(4'-hydroxyphenyl)-2-butanone-4'-O-β-D-glucopyranoside (8), amabiloside (9), N-trans-feruloyl tyramine (10), chrysophanol (11), aloe-emodin (12), emodin (13), physcion (14), physcion-1-O-β-D-glucopyranoside (15), emodin-8-O-β-D-glucopyranoside (16), D-catechin (17) and gallic acid (18). Their structures were determined by combined spectroscopic methods and by comparison of their spectral data with those reported in literature. Compounds 1-10 were tested for their ability to scavenge 1, 1-diphenyl-2-picrylhydrazyl (DPPH) radical.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Chemical structures of compounds 118.
Figure 2
Figure 2
Main HMBC (indicated by blue arrows from 1H to 13C) of compound 1.

References

    1. Bao B., Alisa E.G. RHEUM Linnaeus. In: Li A., Bao B., Alisa E.G., Suk-pyo H., John M., Sergei L.M., Hideaki O., Chong-wook P., editors. Flora of China. Volume 5. Science Press & Missouri Botanical Garden; St. Louis, MO, USA: 2003. pp. 277–350.
    1. Xiao P., He L., Wang L. Ethnopharmacologic study of chinese rhubarb. J. Ethnopharmacol. 1984;10:275–293. doi: 10.1016/0378-8741(84)90016-3. - DOI - PubMed
    1. Rokaya M.B., Münzbergová Z., Timsina B., Bhattarai K.R. Rheum australe D. Don: A review of its botany, ethnobotany, phytochemistry and pharmacology. J. Ethnopharmacol. 2012;141:761–774. doi: 10.1016/j.jep.2012.03.048. - DOI - PubMed
    1. Zargar B.A., Masoodi M.H., Ahmed B., Ganie S.A. Phytoconstituents and therapeutic uses of Rheum emodi wall. ex Meissn. Food Chem. 2011;128:585–589. doi: 10.1016/j.foodchem.2011.03.083. - DOI
    1. Liu B., Yang J., Wang S. The chemical constituents in rhubarb rhizomes and roots derived from Rheum emodi Wall. Huaxi Yaoxue Zazhi. 2007;22:33–35.

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