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Case Reports
. 2014:158:A7503.

[A teenager with Prader-Willi syndrome with loss of appetite]

[Article in Dutch]
Annemieke Smorenberg  1 , Nynke H Buter, Robert Mollema, Arnoud C Toornvliet, W W M Wilfried Hack
Affiliations
  • PMID: 25096033
Case Reports

[A teenager with Prader-Willi syndrome with loss of appetite]

[Article in Dutch]
Annemieke Smorenberg et al. Ned Tijdschr Geneeskd. 2014.

Abstract

Background: Prader-Willi syndrome is characterised by hyperphagia and binge eating, without regurgitation.

Case description: We present a 16-year-old girl with Prader-Willi syndrome exhibiting loss of appetite, stomach ache and regurgitation. Gastro-enteritis was suspected. However, she rapidly developed severe septic shock. During emergency surgery, a fully necrotic and ruptured stomach was seen. Despite respiratory, haemodynamic and surgical efforts, the patient died of necrotic intestinal bleeding.

Conclusion: Binge eating or deviant gastric homeostasis could account for the relatively high incidence of gastric necrosis in patients with Prader-Willi syndrome. Loss of appetite and regurgitation in patients with this syndrome should be considered as warning signs of a possible life-threatening disorder.

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