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Case Reports
. 2014 Jun;31(3):197-200.
doi: 10.5114/pdia.2014.40918. Epub 2014 Jun 13.

Juvenile xanthogranuloma: a rare benign histiocytic disorder

Aneta Szczerkowska-Dobosz  1 , Dorota Kozicka  1 , Dorota Purzycka-Bohdan  1 , Wojciech Biernat  2 , Marta Stawczyk  1 , Roman Nowicki  1
Affiliations
Case Reports

Juvenile xanthogranuloma: a rare benign histiocytic disorder

Aneta Szczerkowska-Dobosz et al. Postepy Dermatol Alergol. 2014 Jun.

Abstract

Juvenile xanthogranuloma (JXG) is a rare histiocytic disorder that typically affects children. The clinical presentation of this disease is characterized by single or, rarely, multiple yellow and brown skin nodules, most often found on the face and neck. Internal organ involvement has been sporadically observed in JXG and is associated with an increased risk of serious complications. We report two cases with a small and large nodular form of JXG.

Keywords: Touton cells; histiocytosis; juvenile xanthogranuloma; nodules.

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Figures

Figure 1
Figure 1
Case 1. Yellowish nodular lesion of the chin
Figure 2
Figure 2
Case 1. Uncommon clinical presentation of cutaneous JXG – plaque-like lesion on the buttock
Figure 3
Figure 3
Case 1. Cutaneous infiltrate of histiocytes sparing the epidermis. Note the presence of single multinucleated cell (white arrow) and eosinophils (black arrow) among the histiocytes
Figure 4
Figure 4
Case 2. Small fitted tight nodules on the side of the fourth toe of the right foot
Figure 5
Figure 5
Case 2. Superficial skin biopsy reveals typical appearance of JXG with Touton cell present
See this image and copyright information in PMC

References

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